Santa Fe vs Deportivo Cali | Prediction | Categoria Primera A | 23/09
Colombia - Categoria Primera A
Santa Fe and Deportivo Cali face each other on Wednesday 09.23.2026, at 02:00 (UK Time), in a Categoria Primera A 2026 match. The game will take place at Santa Fe's home ground, the Estadio Nemesio Camacho El Campín (El Coloso de la 57).
Our team of analysts has crafted predictions for the clash between Club Independiente Santa Fe S.A. and Asociación Deportivo Cali, grounded in an in-depth statistical analysis of both sides. We aim to empower bettors with reliable insights, delivering today’s top free betting tip to support smarter, more profitable choices.
APWin predictions for Santa Fe vs Deportivo Cali
With odds already defined by leading bookmakers, our specialists have thoroughly reviewed the key match data. Check out our expert prediction below:
Double Chance: Santa Fe or Draw
Market: Double Chance: Santa Fe or Draw · @ 1.22
Confidence
76%
Last updated: 20-09-2026
The APWin team has examined the key betting markets and identified the most valuable opportunities.
Our prediction is: Santa Fe to win the 1st half
As the odds and the statistics clearly indicate, Santa Fe is the superior side in this matchup. They play an aggressive attacking style that puts pressure on their opponents. We expect more or less the same gameplan at home against Deportivo Cali, which should result in a fast start.
That is why we are tipping Santa Fe to win the first half in the half-time market.
Our prediction is: Both teams to score
The best betting option for Santa Fe vs Deportivo Cali is the Both Teams to Score market - BTTS. After all, both teams need to seek victory and shouldn't 'park the bus' waiting for the opponent.
But that's not the only reason we believe in a game with goals for both teams. We also see value odds in the BTTS market when we have two offensive teams, as is the case with Santa Fe and Deportivo Cali in this game.
To guarantee a win on Both Teams to Score, as the name suggests, we need both Santa Fe and Deportivo Cali to score goals.
Santa Fe preview
Santa Fe heads into the match with the following record in the Categoria Primera A: in 32 matches, Club Independiente Santa Fe S.A. secured 12 victories, 15 draws, and 5 losses, maintaining an average of 1.59 points per game.
Taking a broader look at Red Express's 2026 season, the team has achieved a total of 17 victories so far.
Santa Fe has been effective in the offence, scoring a total of 65 goals, of which 51 were scored in the Categoria Primera A, resulting in an average of 1.59 goals per game.
Individually, the standout performer is Hugo Rodallega Martínez, who has found the back of the net 14 times. However, he is not alone in driving the offence. Omar Andrés Fernández Frasica has taken on the role of the team's main playmaker, leading with 8 assists.
On the defensive side, Santa Fe has conceded 34 goals in the Categoria Primera A (an average of 1.06 per game) and 44 goals throughout the entire season, with an average of 0.98 per match in the 2026 campaign.
- 19 Sept 2026AlianzaSanta FeW1419 Sept 2026Categoria Primera AAlianza
v.s
Santa Fe1 - 4W - 15 Sept 2026VascoSanta FeL2015 Sept 2026Copa SudamericanaVasco
v.s
Santa Fe2 - 0L - 12 Sept 2026Santa FeDeportes TolimaW1012 Sept 2026Categoria Primera ASanta Fe
v.s
Deportes Tolima1 - 0W - 08 Sept 2026Santa FeVascoD0008 Sept 2026Copa SudamericanaSanta Fe
v.s
Vasco0 - 0D - 05 Sept 2026Santa FeFortaleza CEIFD2205 Sept 2026Categoria Primera ASanta Fe
v.s
Fortaleza CEIF2 - 2D
Deportivo Cali preview
Deportivo Cali comes into the game with 28 matches played so far in the Categoria Primera A. They have secured 11 victories, 9 draws, and 8 losses, maintaining an average of 1.5 points per game in the competition.
Across all competitions in the 2026 season, the team has recorded 15 wins, 9 draws, and 9 losses.
Asociación Deportivo Cali's attack has been highly effective, scoring 44 goals during this period. Of that total, 34 were netted in the Categoria Primera A, with an average of 1.21 goals per game. The overall season average is 1.33.
Los Azucareros's offensive system is led by Steven Andrés Rodríguez Ossa, the team's top scorer this season. The colombian forward has found the back of the net 10 times. He is supported by the team's best assist provider, Johan Andrés Martínez. The forward has contributed with 6 assists.
On the defensive side, the team has conceded 24 goals with an average of 0.86 per game in the championship. For the whole season, the team conceded 29 goals in 33 matches, averaging 0.88 per match.
- 19 Sept 2026Deportivo CaliCúcuta DeportivoW3019 Sept 2026Categoria Primera ADeportivo Cali
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Cúcuta Deportivo3 - 0W - 13 Sept 2026Once CaldasDeportivo CaliW1213 Sept 2026Categoria Primera AOnce Caldas
v.s
Deportivo Cali1 - 2W - 11 Sept 2026MillonariosDeportivo CaliD1111 Sept 2026Categoria Primera AMillonarios
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Deportivo Cali1 - 1D - 08 Sept 2026Atlético NacionalDeportivo CaliL3008 Sept 2026Copa ColombiaAtlético Nacional
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Deportivo Cali3 - 0L - 31 Aug 2026Deportivo CaliAtlético BucaramangaD1131 Aug 2026Categoria Primera ADeportivo Cali
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Atlético Bucaramanga1 - 1D
Head to head: Santa Fe vs Deportivo Cali
Review the head-to-head record between the teams, featuring key data to support your match prediction.
Santa Fe
Home
Deportivo Cali
Away
Points & Results
- PPG1.591.50
- 38%Wins39%
- 53%First to Score57%
Goals Scored & Conceded
- Scored/game1.591.21
- Conceded/game1.060.86
- xG1.401.39
- xGA1.421.19
Trends
- 72%Both Score46%
- 22%Clean Sheet36%
- 13%Failed to Score25%
Access all match stats for Santa Fe vs Deportivo Cali
Where to watch Santa Fe vs Deportivo Cali live?
Check out the live stream of Santa Fe vs Deportivo Cali below and follow the match in real time.
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Santa Fe vs Deportivo Cali
Likely Scores
| # | Score | Probability | % |
|---|---|---|---|
| 1 | 1 - 1 | 0.14% | |
| 2 | 0 - 0 | 0.09% | |
| 3 | 0 - 1 | 0.09% | |
| 4 | 1 - 0 | 0.09% | |
| 5 | 1 - 2 | 0.08% | |
| 6 | 2 - 1 | 0.08% | |
| 7 | 0 - 2 | 0.06% | |
| 8 | 2 - 0 | 0.06% | |
| 9 | 2 - 2 | 0.05% | |
| 10 | 1 - 3 | 0.03% | |
| 11 | 3 - 1 | 0.03% | |
| 12 | 0 - 3 | 0.03% |