RSC Anderlecht and Lyon face each other in an official match of the 2026/27 Europa League season. The game takes place at Lotto Park (Constant Vanden Stock Stadium) on Wednesday, 16/09/2026, at 20:00 (UK Time).

Our experts have prepared predictions for Royal Sporting Club Anderlecht vs Olympique Lyonnais, based on a detailed statistical review of both teams. Our goal is to assist bettors in making profitable decisions, which is why we offer the best free prediction for today.

APWin predictions for RSC Anderlecht vs Lyon

The top bookmakers have set the odds, and our team has analysed all relevant match data. See our expert match prediction below:

APWin Prediction

Double Chance: RSC Anderlecht or Draw

APWin experts have analysed the main betting markets and selected high-value bets.

👉 Our prediction is: Over 2.5 goals in the match

RSC Anderlecht and Lyon are two attacking sides who have what it takes to make this an entertaining and eventful match.

That's why we highly recommend taking the bet of over 2.5 goals. The bet wins if there are 3 or more goals scored in the match, and if there are 2 goals or fewer, the bet loses.

👉 Our prediction is: Both teams don't score

Based on our analysis, we are confident that the best bet is to go 'no' on the Both Teams to Score market.

The matchup figures to be a tight, defensive one, with both teams desperate not to get caught out. That's why we see only one or none of the teams finding the back of the net in this encounter, which are the conditions needed to win the bet.

Purple & White preview

RSC Anderlecht comes into the match having played 6 games in the Europa League so far. They have recorded 5 wins, 1 draws, and 0 losses, with an average of 2.67 points per game in the tournament.

In the 2026/27 season across all competitions, the team has achieved 25 wins, 14 draws, and 19 losses.

RSC Anderlecht's attack has scored 84 goals during this period. Out of this total, 14 goals were scored in the Europa League, averaging 2.33 goals per match. The season's average stands at 1.45.

The offence system of RSC Anderlecht is led by Thorgan Hazard as the top scorer of the season. The belgian midfielder has scored 13 goals. He is supported by the season's best assistant, Thorgan Hazard, who has contributed with 7 assists.

On the defensive side, the team has conceded 4 goals with an average of 0.67 in the league. In all competitions, the current numbers are 77 goals conceded in 58 matches, resulting in an average of 1.33.

The Gones preview

On the other hand, Lyon comes into the match having played 0 games in the Europa League so far. They have recorded 0 wins, 0 draws, and 0 losses, with an average of 0 points per game in the tournament.

In the 2026/27 season across all competitions, the team has achieved 31 wins, 11 draws, and 14 losses.

Lyon's attack has scored 93 goals during this period. Out of this total, 0 goals were scored in the Europa League, averaging 0 goals per match. The season's average stands at 1.66.

The offence system of Lyon is led by Corentin Tolisso as the top scorer of the season. The french midfielder has scored 11 goals. He is supported by the season's best assistant, Afonso Bastardo Moreira, who has contributed with 7 assists.

On the defensive side, the team has conceded 0 goals with an average of 0 in the league. In all competitions, the current numbers are 58 goals conceded in 56 matches, resulting in an average of 1.04.

Head to head: RSC Anderlecht vs Lyon

Review the head-to-head record between the teams, featuring key data to support your match prediction.

Home Team

RSC Anderlecht Team Logo

RSC Anderlecht

Europe - UEFA Europa League

Form Last 5 PPG
Overall W D W L W

2

Home D W W W W

2.6

Away W L W L W

1.8

Away Team

Lyon Team Logo

Lyon

Europe - UEFA Europa League

Form Last 5 PPG
Overall D W D L W

1.6

Home W D L W L

1.4

Away D W D L L

1

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Published on 13 September 2026, at 20:10 Last updated on 13 September 2026, at 20:10
Author: Gustavo Porto

Sports betting analyst with over ten years of experience in football analysis, match statistics and betting markets.