Independiente Medellín and Santa Fe face each other in an official match of the 2025 Categoria Primera A season. The game takes place at Estadio Atanasio Girardot on Tuesday, 21/10/2025, at 02:10 (UK Time).

Our experts have prepared predictions for Independiente Medellín vs Santa Fe, based on detailed statistical review of both teams. Our goal is to assist bettors in making profitable decisions, which is why we offer the best free prediction for today.

APWin predictions for Independiente Medellín vs Santa Fe

The top bookmakers have set the odds, and our team has analyzed all relevant match data. See our expert match prediction below:

APWin Prediction

Independiente Medellín Win

APWin experts have analyzed the main betting markets and selected high-value bets.

👉 Our prediction is: Independiente Medellín to win

Based on our evaluations, Independiente Medellín vs Santa Fe is a matchup between two evenly matched sides. But playing at home gives Independiente Medellín the added advantage, which is why we recommend taking Independiente Medellín to win outright at home.

The odds offered for a Independiente Medellín win have a lot of value, and the fact that they have that home support should help tremendously in their bid to get the victory.

Independiente Medellín preview

Independiente Medellín comes into the match having played 43 games in the Categoria Primera A so far. They have recorded 21 wins, 14 draws, and 8 losses, with an average of 1.79 points per game in the tournament.

In the 2025 season across all competitions, the team has achieved 24 wins, 17 draws, and 9 losses.

Independiente Medellín's attack has scored 71 goals during this period. Out of this total, 62 goals were scored in the Categoria Primera A, averaging 1.44 goals per match. The season's average stands at 1.42.

The offense system of Independiente Medellín is led by Francisco Fydriszewski as the top scorer of the season. The argentinian forward has scored 12 goals. He is supported by the season's best assistant, Brayan Léon Muñiz, who has contributed with 9 assists.

On the defensive side, the team has conceded 38 goals with an average of 0.88 in the league. In all competitions, the current numbers are 43 goals conceded in 50 matches, resulting in an average of 0.86.

Santa Fe preview

On the other hand, Santa Fe comes into the match having played 43 games in the Categoria Primera A so far. They have recorded 19 wins, 13 draws, and 11 losses, with an average of 1.63 points per game in the tournament.

In the 2025 season across all competitions, the team has achieved 24 wins, 16 draws, and 14 losses.

Santa Fe's attack has scored 70 goals during this period. Out of this total, 54 goals were scored in the Categoria Primera A, averaging 1.26 goals per match. The season's average stands at 1.3.

The offense system of Santa Fe is led by Hugo Rodallega Martínez as the top scorer of the season. The colombian forward has scored 18 goals. He is supported by the season's best assistant, Hárold Santiago Mosquera Caicedo, who has contributed with 9 assists.

On the defensive side, the team has conceded 44 goals with an average of 1.02 in the league. In all competitions, the current numbers are 57 goals conceded in 54 matches, resulting in an average of 1.06.

Head to head: Independiente Medellín vs Santa Fe

Review the head-to-head record between the teams, featuring key data to support your match prediction.

Home Team

Independiente Medellín Team Logo

Independiente Medellín

Colombia - Categoria Primera A

Form Last 5 PPG
Overall W W L W D

1.79

Home W D D W W

1.81

Away W L W W W

1.77

Away Team

Santa Fe Team Logo

Santa Fe

Colombia - Categoria Primera A

Form Last 5 PPG
Overall D L W D W

1.63

Home L W W L W

1.62

Away D D D L L

1.64

Access all match stats for Independiente Medellín vs Santa Fe

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