Cusco FC vs Independiente Medellín | Prediction | Copa Libertadores | 21/05

South America - Copa Libertadores

2 - 3

20 May 2026 22:00

Cusco FC and Independiente Medellín face each other on Thursday 05.21.2026, at 03:00 (UK Time), in a Copa Libertadores 2026 match. The game will take place at Cusco FC's home ground, the Estadio Inca Garcilaso de la Vega.

Our team of analysts has crafted predictions for the clash between Cusco Fútbol Club and El Equipo del Pueblo S.A., grounded in an in-depth statistical analysis of both sides. We aim to empower bettors with reliable insights, delivering today’s top free betting tip to support smarter, more profitable choices.

APWin predictions for Cusco FC vs Independiente Medellín

With odds already defined by leading bookmakers, our specialists have thoroughly reviewed the key match data. Check out our expert prediction below:

No BTTS 2nd Half

Market: No BTTS 2nd Half · @ 1.35

1.35

Last updated: 17-05-2026

The APWin team has examined the key betting markets and identified the most valuable opportunities.

Our prediction is: Independiente Medellín to win

Take Independiente Medellín lightly at your own risk. While they are playing away from home, they are still a dangerous opponent that is capable of causing an upset.

Indeed, we are tipping Independiente Medellín to win outright on the 1X2 market, where they are priced at 2.65 to win. We see Independiente Medellín matching up well with Cusco FC, and they have some weapons that can exploit the home side's vulnerabilities.

Our prediction is: Both teams don't score

Based on our analysis, we are confident that the best bet is to go 'no' on the Both Teams to Score market.

The matchup figures to be a tight, defensive one, with both teams desperate not to get caught out. That's why we see only one or none of the teams finding the back of the net in this encounter, which are the conditions needed to win the bet.

Cusco FC preview

Cusco FC heads into the match with the following record in the Copa Libertadores: in 4 matches, Cusco Fútbol Club secured 0 victories, 1 draws, and 3 losses, maintaining an average of 0.25 points per game.

Taking a broader look at Golden Ones's 2026 season, the team has achieved a total of 6 victories so far.

Cusco FC has been effective in the offence, scoring a total of 20 goals, of which 2 were scored in the Copa Libertadores, resulting in an average of 0.5 goals per game.

Individually, the standout performer is Facundo Julián Callejo, who has found the back of the net 8 times. However, he is not alone in driving the offence. José Miguel Manzaneda Pineda has taken on the role of the team's main playmaker, leading with 5 assists.

On the defensive side, Cusco FC has conceded 6 goals in the Copa Libertadores (an average of 1.5 per game) and 29 goals throughout the entire season, with an average of 1.53 per match in the 2026 campaign.

Cusco FC's Latest Results

Independiente Medellín preview

Independiente Medellín comes into the game with 7 matches played so far in the Copa Libertadores. They have secured 3 victories, 3 draws, and 1 losses, maintaining an average of 1.71 points per game in the competition.

Across all competitions in the 2026 season, the team has recorded 11 wins, 9 draws, and 8 losses.

El Equipo del Pueblo S.A.'s attack has been highly effective, scoring 36 goals during this period. Of that total, 8 were netted in the Copa Libertadores, with an average of 1.14 goals per game. The overall season average is 1.29.

Poderoso de la Montaña's offensive system is led by José Ortiz, the team's top scorer this season. The colombian defender has found the back of the net 4 times. He is supported by the team's best assist provider, Francisco Javier Chaverra Angulo. The forward has contributed with 2 assists.

On the defensive side, the team has conceded 8 goals with an average of 1.14 per game in the championship. For the whole season, the team conceded 33 goals in 28 matches, averaging 1.18 per match.

Independiente Medellín's Latest Results