Santa Fe and América de Cali face each other on Wednesday 05.13.2026, at 02:30 (UK Time), in a Categoria Primera A 2026 match. The game will take place at Santa Fe's home ground, the Estadio Nemesio Camacho El Campín.

Our team of analysts has crafted predictions for the clash between Club Independiente Santa Fe S.A. and Sociedad Anónima Deportiva América de Cali S.A., grounded in an in-depth statistical analysis of both sides. We aim to empower bettors with reliable insights, delivering today’s top free betting tip to support smarter, more profitable choices.

APWin predictions for Santa Fe vs América de Cali

With odds already defined by leading bookmakers, our specialists have thoroughly reviewed the key match data. Check out our expert prediction below:

APWin Prediction

Santa Fe Win

The APWin team has examined the key betting markets and identified the most valuable opportunities.

👉 Our prediction is: Both teams don't score

Defensive solidity should prove to be a major factor in this matchup. Both teams' backlines are rock solid, so scoring chances will be hard to come by.

As such, there is decent value to be had in betting 'no' on the Both Teams to Score market.

👉 Our prediction is: Santa Fe to win

Santa Fe to win is our top betting tip for this upcoming match against América de Cali. Santa Fe's odds in the online betting sites have them heavily favoured at home, where they have been quite strong all season.

And our expert analysts fancy their chances as well given their current form and overall statistics.

Santa Fe preview

Santa Fe heads into the match with the following record in the Categoria Primera A: in 20 matches, Club Independiente Santa Fe S.A. secured 7 victories, 9 draws, and 4 losses, maintaining an average of 1.5 points per game.

Taking a broader look at Red Express's 2026 season, the team has achieved a total of 7 victories so far.

Santa Fe has been effective in the offence, scoring a total of 33 goals, of which 30 were scored in the Categoria Primera A, resulting in an average of 1.5 goals per game.

Individually, the standout performer is Hugo Rodallega Martínez, who has found the back of the net 8 times. However, he is not alone in driving the offence. Omar Andrés Fernández Frasica has taken on the role of the team's main playmaker, leading with 7 assists.

On the defensive side, Santa Fe has conceded 23 goals in the Categoria Primera A (an average of 1.15 per game) and 29 goals throughout the entire season, with an average of 1.21 per match in the 2026 campaign.

América de Cali preview

América de Cali comes into the game with 20 matches played so far in the Categoria Primera A. They have secured 10 victories, 4 draws, and 6 losses, maintaining an average of 1.7 points per game in the competition.

Across all competitions in the 2026 season, the team has recorded 13 wins, 5 draws, and 7 losses.

Sociedad Anónima Deportiva América de Cali S.A.'s attack has been highly effective, scoring 33 goals during this period. Of that total, 26 were netted in the Categoria Primera A, with an average of 1.3 goals per game. The overall season average is 1.32.

Los Diablos Rojos's offensive system is led by Yeison Estiven Guzmán Gómez, the team's top scorer this season. The colombian midfielder has found the back of the net 10 times. He is supported by the team's best assist provider, Rafael Carrascal. The midfielder has contributed with 6 assists.

On the defensive side, the team has conceded 16 goals with an average of 0.8 per game in the championship. For the whole season, the team conceded 21 goals in 25 matches, averaging 0.84 per match.

Head to head: Santa Fe vs América de Cali

Review the head-to-head record between the teams, featuring key data to support your match prediction.

Home Team

Santa Fe Team Logo

Santa Fe

Colombia - Categoria Primera A

Form Last 5 PPG
Overall D D W L W

1.6

Home D W W D L

1.6

Away D L W L D

1

Away Team

América de Cali Team Logo

América de Cali

Colombia - Categoria Primera A

Form Last 5 PPG
Overall D W W L L

1.4

Home D W W W W

2.6

Away W L L W D

1.4

Access all match stats for Santa Fe vs América de Cali

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Published on 10 May 2026, at 20:07 Last updated on 10 May 2026, at 20:07