Peñarol and Santa Fe face each other in an official match of the 2026 Copa Libertadores season. The game takes place at Estadio Campeón del Siglo on Thursday, 28/05/2026, at 01:30 (UK Time).

Our experts have prepared predictions for Club Atlético Peñarol vs Club Independiente Santa Fe S.A., based on a detailed statistical review of both teams. Our goal is to assist bettors in making profitable decisions, which is why we offer the best free prediction for today.

APWin predictions for Peñarol vs Santa Fe

The top bookmakers have set the odds, and our team has analysed all relevant match data. See our expert match prediction below:

APWin Prediction

Under 2.5 Goals

APWin experts have analysed the main betting markets and selected high-value bets.

👉 Our prediction is: Peñarol win or draw

The match is an evenly balanced affair with very little difference between the two sides. But the added benefit of home advantage is enough to tilt the scales in Peñarol's favour.

We recommend betting on Peñarol to win or draw on the Double Chance market. Since they will be playing in front of their home fans, that should give them that extra boost they need to avoid defeat, which is the only condition to win the bet.

Coalmen preview

Peñarol comes into the match having played 5 games in the Copa Libertadores so far. They have recorded 0 wins, 3 draws, and 2 losses, with an average of 0.6 points per game in the tournament.

In the 2026 season across all competitions, the team has achieved 10 wins, 6 draws, and 7 losses.

Peñarol's attack has scored 31 goals during this period. Out of this total, 4 goals were scored in the Copa Libertadores, averaging 0.8 goals per match. The season's average stands at 1.35.

The offence system of Peñarol is led by Douglas Matías Arezo Martínez as the top scorer of the season. The uruguayan forward has scored 7 goals. He is supported by the season's best assistant, Leonardo Cecilio Fernández López, who has contributed with 2 assists.

On the defensive side, the team has conceded 7 goals with an average of 1.4 in the league. In all competitions, the current numbers are 25 goals conceded in 23 matches, resulting in an average of 1.09.

Red Express preview

On the other hand, Santa Fe comes into the match having played 5 games in the Copa Libertadores so far. They have recorded 1 wins, 2 draws, and 2 losses, with an average of 1 points per game in the tournament.

In the 2026 season across all competitions, the team has achieved 10 wins, 13 draws, and 6 losses.

Santa Fe's attack has scored 41 goals during this period. Out of this total, 5 goals were scored in the Copa Libertadores, averaging 1 goals per match. The season's average stands at 1.41.

The offence system of Santa Fe is led by Hugo Rodallega Martínez as the top scorer of the season. The colombian forward has scored 12 goals. He is supported by the season's best assistant, Omar Andrés Fernández Frasica, who has contributed with 8 assists.

On the defensive side, the team has conceded 7 goals with an average of 1.4 in the league. In all competitions, the current numbers are 31 goals conceded in 29 matches, resulting in an average of 1.07.

Head to head: Peñarol vs Santa Fe

Review the head-to-head record between the teams, featuring key data to support your match prediction.

Home Team

Peñarol Team Logo

Peñarol

South America - Copa Libertadores

Form Last 5 PPG
Overall W D W W D

2.2

Home D W D D L

1.2

Away W W D L L

1.4

Away Team

Santa Fe Team Logo

Santa Fe

South America - Copa Libertadores

Form Last 5 PPG
Overall D W D W D

1.8

Home W D W D W

2.2

Away D D L W L

1

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Published on 25 May 2026, at 20:03 Last updated on 5 August 2026, at 20:00
Author: Amauri Barbosa

Sports betting analyst with over 15 years of experience. At APWin, he writes football predictions, reviews bookmakers and explains the reasoning behind every bet.