América de Cali and Santa Fe face each other on Sunday 05.10.2026, at 02:20 (UK Time), in a Categoria Primera A 2026 match. The game will take place at América de Cali's home ground, the Estadio Olímpico Pascual Guerrero.

Our team of analysts has crafted predictions for the clash between Sociedad Anónima Deportiva América de Cali S.A. and Club Independiente Santa Fe S.A., grounded in an in-depth statistical analysis of both sides. We aim to empower bettors with reliable insights, delivering today’s top free betting tip to support smarter, more profitable choices.

APWin predictions for América de Cali vs Santa Fe

With odds already defined by leading bookmakers, our specialists have thoroughly reviewed the key match data. Check out our expert prediction below:

APWin Prediction

No BTTS 2nd Half

The APWin team has examined the key betting markets and identified the most valuable opportunities.

👉 Our prediction is: Over 2.5 goals in the match

América de Cali vs Santa Fe has all the makings of a high-scoring affair, and we anticipate this game going over 2.5 goals.

Online bookmakers have given good 1.98 odds for over 2.5 goals, and we fancy the chances of that bet paying off thanks to the tremendous attacking ability of the two teams.

👉 Our prediction is: América de Cali to win

América de Cali vs Santa Fe has all the makings of a competitive battle between two sides that are both eyeing an important win. But we are ever so slightly leaning toward América de Cali to win on the 1X2 market.

América de Cali will enjoy home advantage, which they have capitalised on with their strong form at home. They remain good value to win with their odds, and we expect them to pay out those odds with all three points at home.

América de Cali preview

América de Cali heads into the match with the following record in the Categoria Primera A: in 19 matches, Sociedad Anónima Deportiva América de Cali S.A. secured 10 victories, 3 draws, and 6 losses, maintaining an average of 1.74 points per game.

Taking a broader look at Los Diablos Rojos's 2026 season, the team has achieved a total of 13 victories so far.

América de Cali has been effective in the offence, scoring a total of 32 goals, of which 25 were scored in the Categoria Primera A, resulting in an average of 1.32 goals per game.

Individually, the standout performer is Yeison Estiven Guzmán Gómez, who has found the back of the net 10 times. However, he is not alone in driving the offence. Rafael Carrascal has taken on the role of the team's main playmaker, leading with 5 assists.

On the defensive side, América de Cali has conceded 15 goals in the Categoria Primera A (an average of 0.79 per game) and 20 goals throughout the entire season, with an average of 0.83 per match in the 2026 campaign.

Santa Fe preview

Santa Fe comes into the game with 19 matches played so far in the Categoria Primera A. They have secured 7 victories, 8 draws, and 4 losses, maintaining an average of 1.53 points per game in the competition.

Across all competitions in the 2026 season, the team has recorded 7 wins, 10 draws, and 6 losses.

Club Independiente Santa Fe S.A.'s attack has been highly effective, scoring 32 goals during this period. Of that total, 29 were netted in the Categoria Primera A, with an average of 1.53 goals per game. The overall season average is 1.39.

Red Express's offensive system is led by Hugo Rodallega Martínez, the team's top scorer this season. The colombian forward has found the back of the net 7 times. He is supported by the team's best assist provider, Omar Andrés Fernández Frasica. The forward has contributed with 7 assists.

On the defensive side, the team has conceded 22 goals with an average of 1.16 per game in the championship. For the whole season, the team conceded 28 goals in 23 matches, averaging 1.22 per match.

Head to head: América de Cali vs Santa Fe

Review the head-to-head record between the teams, featuring key data to support your match prediction.

Home Team

América de Cali Team Logo

América de Cali

Colombia - Categoria Primera A

Form Last 5 PPG
Overall W W L L W

1.8

Home W W W W D

2.6

Away W L L W D

1.4

Away Team

Santa Fe Team Logo

Santa Fe

Colombia - Categoria Primera A

Form Last 5 PPG
Overall D W L W W

2

Home D W W D L

1.6

Away L W L D D

1

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Published on 7 May 2026, at 20:09 Last updated on 7 May 2026, at 20:09