Santos Laguna and Atlético San Luis face each other in an official match of the 2025/26 Liga MX season. The game takes place at Estadio Nuevo Corona on Monday, 22/09/2025, at 00:00 (UK Time).

Our experts have prepared predictions for Santos Laguna vs Atlético San Luis, based on detailed statistical review of both teams. Our goal is to assist bettors in making profitable decisions, which is why we offer the best free prediction for today.

APWin predictions for Santos Laguna vs Atlético San Luis

The top bookmakers have set the odds, and our team has analyzed all relevant match data. See our expert match prediction below:

APWin Prediction

2nd Half Under 1.5 Goals

APWin experts have analyzed the main betting markets and selected high-value bets.

👉 Our prediction is: Atlético San Luis to win

While Atlético San Luis will head into their match against Santos Laguna as the favourite, it is still far from a sure thing to score three points away from home. Nevertheless, our betting tip is still Atlético San Luis to win on the 1X2 market.

Our analysis of Atlético San Luis leads us to believe that they are quite capable on their travels and can come up with the away win without much trouble, even against a tricky opponent like Santos Laguna.

👉 Our prediction is: Santos Laguna to win the 1st half

Our top betting tip for the Santos Laguna vs Atlético San Luis match is Santos Laguna to win the first half. While the half-time market is not one of the more well-known betting markets, it often offers better value odds than wins over 90 minutes.

We see this value in Santos Laguna, which has been in impressive form at home and regularly gets out to quick starts. They should have a favourable matchup against Atlético San Luis, who have had their share of struggles of late.

Santos Laguna preview

Santos Laguna comes into the match having played 8 games in the Liga MX so far. They have recorded 2 wins, 1 draws, and 5 losses, with an average of 0.88 points per game in the tournament.

In the 2025/26 season across all competitions, the team has achieved 4 wins, 1 draws, and 5 losses.

Santos Laguna's attack has scored 17 goals during this period. Out of this total, 11 goals were scored in the Liga MX, averaging 1.38 goals per match. The season's average stands at 1.7.

The offense system of Santos Laguna is led by Cristian Dájome as the top scorer of the season. The colombian forward has scored 3 goals. He is supported by the season's best assistant, Aldo López Vargas, who has contributed with 2 assists.

On the defensive side, the team has conceded 13 goals with an average of 1.63 in the league. In all competitions, the current numbers are 13 goals conceded in 10 matches, resulting in an average of 1.3.

Atlético San Luis preview

On the other hand, Atlético San Luis comes into the match having played 8 games in the Liga MX so far. They have recorded 2 wins, 1 draws, and 5 losses, with an average of 0.88 points per game in the tournament.

In the 2025/26 season across all competitions, the team has achieved 4 wins, 1 draws, and 5 losses.

Atlético San Luis's attack has scored 13 goals during this period. Out of this total, 11 goals were scored in the Liga MX, averaging 1.38 goals per match. The season's average stands at 1.3.

The offense system of Atlético San Luis is led by João Pedro Geraldino dos Santos Galvão as the top scorer of the season. The italian forward has scored 6 goals. He is supported by the season's best assistant, Mateo Klimowicz, who has contributed with 2 assists.

On the defensive side, the team has conceded 14 goals with an average of 1.75 in the league. In all competitions, the current numbers are 14 goals conceded in 10 matches, resulting in an average of 1.4.

Head to head: Santos Laguna vs Atlético San Luis 

Review the head-to-head record between the teams, featuring key data to support your match prediction.

Home Team

Santos Laguna Team Logo

Santos Laguna

Mexico - Liga MX

Form Last 5 PPG
Overall D L L L L

0.88

Home L W W L L

1.5

Away D L L L L

0.25

Away Team

Atlético San Luis Team Logo

Atlético San Luis

Mexico - Liga MX

Form Last 5 PPG
Overall D L L L W

0.88

Home D L L L L

0.25

Away L L W W L

1.5

Access all match stats for Santos Laguna vs Atlético San Luis

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