Independiente Medellín and Santa Fe face each other on Thursday 09.25.2025, at 00:00 (UK Time), in a Copa Colombia 2025 match. The game will take place at Independiente Medellín's home ground, the Estadio Atanasio Girardot.
Our team of analysts has crafted predictions for the clash between Independiente Medellín and Santa Fe, grounded in an in-depth statistical analysis of both sides. We aim to empower bettors with reliable insights, delivering today’s top free betting tip to support smarter, more profitable choices.
APWin predictions for Independiente Medellín vs Santa Fe
With odds already defined by leading bookmakers, our specialists have thoroughly reviewed the key match data. Check out our expert prediction below:
BTTS - No
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Independiente Medellín preview
Independiente Medellín heads into the match with the following record in the Copa Colombia: in 4 matches, El Rojo Paisa secured 2 victories, 2 draws, and 0 losses, maintaining an average of 2 points per game.
Taking a broader look at Independiente Medellín's 2025 season, the team has achieved a total of 20 victories so far.
Independiente Medellín has been effective in the offense, scoring a total of 54 goals, of which 4 were scored in the Copa Colombia, resulting in an average of 1 goals per game.
Individually, the standout performer is Francisco Fydriszewski, who has found the back of the net 9 times. However, he is not alone in driving the offense. Brayan Léon Muñiz has taken on the role of the team's main playmaker, leading with 6 assists.
On the defensive side, Independiente Medellín has conceded 2 goals in the Copa Colombia (an average of 0.5 per game) and 34 goals throughout the entire season, with an average of 0.79 per match in the 2025 campaign.
Santa Fe preview
Santa Fe comes into the game with 4 matches played so far in the Copa Colombia. They have secured 2 victories, 2 draws, and 0 losses, maintaining an average of 2 points per game in the competition.
Across all competitions in the 2025 season, the team has recorded 21 wins, 14 draws, and 11 losses.
Santa Fe's attack has been highly effective, scoring 60 goals during this period. Of that total, 7 were netted in the Copa Colombia, with an average of 1.75 goals per game. The overall season average is 1.3.
Santa Fe's offensive system is led by Hugo Rodallega Martínez, the team's top scorer this season. The colombian forward has found the back of the net 16 times. He is supported by the team's best assist provider, Omar Andrés Fernández Frasica. The forward has contributed with 8 assists.
On the defensive side, the team has conceded 2 goals with an average of 0.5 per game in the championship. For the whole season, the team conceded 46 goals in 46 matches, averaging 1 per match.
Head to head: Independiente Medellín vs Santa Fe
Review the head-to-head record between the teams, featuring key data to support your match prediction.
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